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Association between nocturnal falls and hypnotic drug use in older patients at acute care hospitals

期刊: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 2023; 79 (6)

PurposeAlthough hypnotic drug use is a known risk factor for falls, few reports have analyzed fall risk associated with individual hypnotic drugs afte......

Incidence and risk factors of drug-induced kidney injury in children: a systematic review and meta-analysis

期刊: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 2023; 79 (12)

PurposeTo comprehensively summarize the incidence and risk factors of drug-induced kidney injury (DIKI) in children.MethodsWe systematically searched ......

Mechanisms of landiolol-mediated positive inotropy in critical care settings

期刊: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 2023; 79 (12)

PurposeTo present the potential mechanisms by which landiolol enhances a positive inotropic response in critically ill patients.MethodsAnalysis of pre......

Beyond benzodiazepines: a meta-analysis and narrative synthesis of the efficacy and safety of alternative options for alcohol withdrawal syndrome management

期刊: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 2023; 79 (9)

PurposeTo compare the efficacy and safety of non-benzodiazepines (non-BZDs) to benzodiazepines (BZDs) in the treatment of alcohol withdrawal syndrome ......

Buprenorphine plasma and cerebrospinal fluid concentrations in osteoarthritis patients during low-dose transdermal patch dosing

期刊: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 2023; 79 (12)

MethodsFifty-six (56) patients scheduled for arthroplasty, received 7-day extended-release buprenorphine transdermal patches (5 mu g/h) for five conse......

Patients with bariatric surgery: Urgent need for accurate registration of the contraindication to enable safe pharmacotherapy in hospital and primary care

期刊: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 2023; 79 (2)

Purpose To enable the use of automatic clinical decision support for pharmacotherapy in patients with bariatric surgery, it is necessary to register t......

Cost-utility analysis of a structured medication review compared to usual care in Parkinson's disease

期刊: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 2023; 79 (2)

Purpose For controlling symptoms in Parkinson's disease (PD) together with treating additional comorbidities, patients often face complex medication r......

Linezolid pharmacokinetics: a systematic review for the best clinical practice

期刊: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 2023; 79 (2)

Objectives To summarize the pharmacokinetics of linezolid to optimize the dosing regimen in special populations. Methods A literature search was perfo......

Long-term outcomes of statin dose, class, and use intensity on primary prevention of cardiovascular mortality: a national T2DM cohort study

期刊: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 2023; 79 (5)

PurposeTo investigate how statins reduce cardiovascular mortality in patients with type 2 diabetes (T2DM) in a dose-, class-, and use intensity-depend......

Costs associated with adverse drug reactions in an older population admitted to hospital: a prospective cohort study

期刊: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 2023; 79 (10)

PurposeThis study examines healthcare costs associated with adverse drug reactions (ADR) in an older population admitted acutely to an Irish tertiary ......

The risk of congenital heart defects associated with corticosteroids use during the first trimester of pregnancy: a systematic review and meta-analysis

期刊: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 2023; 79 (1)

Background Prior studies have suggested that maternal corticosteroids exposure during the first trimester may be associated with an increased risk of ......

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